Multi-Agent Framework

AutoGen

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Open-source multi-agent framework (Python/.NET) with AgentChat and Studio

AutoGen is Microsoft's open-source framework for building agentic applications with your own model API keys. The current stable release (python v0.7.5, Sep 30 2025) ships a layered architecture: Core for event-driven message passing across Python and .NET runtimes, AgentChat for common multi-agent patterns, Extensions for model/tool connectors (OpenAI and Azure OpenAI, Anthropic, Gemini via OpenAI-compatible endpoints, and local models via Ollama), plus AutoGen Studio for no-code multi-agent prototyping and AutoGen Bench for evaluation. It's MIT-licensed and maintained in the open on GitHub.

CrewAI

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MIT-licensed agents, crews, and flows framework with optional control plane

CrewAI is an MIT-licensed Python framework for multi-agent automations. The 1.6.1 release (Nov 29 2025) ships Crews for autonomous collaboration and Flows for event-driven orchestration with guardrails, memory, knowledge, and observability hooks. It runs with your own model/API keys (OpenAI/Azure OpenAI, Anthropic, OpenAI-compatible providers like Groq, or local via Ollama/LM Studio) and offers an optional Crew Control Plane for hosted/on-prem tracing, triggers, and RBAC.